ANTI-ULCER EFFECT OF NIGELLA SATIVA LINN. AGAINST GASTRIC ULCERS IN RATS

Authors

  • Mohd Wasif Ahmed Department of Pharmacology, AZAD College of Pharmacy, Moinabad, Telangana, India.
  • Roshan.S Department of Pharmacology, AZAD College of Pharmacy, Moinabad, Telangana, India.
  • N.L. Mahammed Department of Pharmacology, AZAD College of Pharmacy, Moinabad, Telangana, India.
  • M A Muqeem Nasir Department of Pharmacology, AZAD College of Pharmacy, Moinabad, Telangana, India.

Keywords:

Nigella Sativa, Pyloric Ligation, Aspirin, Ulcer Index

Abstract

The effect of alcoholic extract of Nigella Sativa was investigated in rats to evaluate the anti-ulcer activity by using two models, i.e. Pyloric ligation and aspirin Induced gastric ulcer. The parameters taken to assess anti ulcer activity were volume of gastric secretion, free acidity, total acidity and ulcer index. The results indicate that the alcoholic extract significantly (P < 0.001) decreases the volume of gastric acid secretion, free acidity, total acidity and ulcer index with respect to control.

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Published

2016-03-15

How to Cite

Ahmed, M. W. ., Roshan.S, Mahammed, N. ., & Nasir , M. A. M. . (2016). ANTI-ULCER EFFECT OF NIGELLA SATIVA LINN. AGAINST GASTRIC ULCERS IN RATS. International Journal of Research and Development in Pharmacy & Life Sciences, 5(2), 2006-2009. Retrieved from https://www.ijrdpl.com/index.php/ijrdpl/article/view/197

Issue

Vol. 5 No. 2 (2016): Volume 5 Issue 2, February - March (2016)

Section

Research
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